Immune Response and Immunomodulatory Effect of Levamisole in Immunosuppressed Dogs Vaccinated against Parvovirosis

نویسندگان

  • JANA MOJŽIŠOVÁ
  • RUDOLF HROMADA
  • ŠTEFAN PAULÍK
  • MILOSLAV ONDRAŠOVIČ
چکیده

The specific and non-specific immune response and immunomodulatory effect of levamisole were studied in dogs with altered immune function due to giardiosis and vaccinated against canine parvovirus (CPV) infection. In immunosuppressed dogs combination of vaccine with levamisole treatment enhanced depressed phagocytic ability and stimulated proliferation activity of lymphocytes. CPV antibody production was one week delayed in dogs with immunosuppression. Marked higher titer of CPV antibodies was found after levamisole application.

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تاریخ انتشار 2004